In 1543, Andreas Vesalius, a pioneering Flemish anatomist, published De Humani Corporis Fabrica (On the Fabric of the Human Body), a groundbreaking work that transformed the understanding of human anatomy.

Vesalius challenged centuries of medical dogma, much of it based on the works of Galen, by conducting accurate dissections of human cadavers and documenting his findings. De Humani Corporis Fabrica was revolutionary for its detailed illustrations and descriptions of the human body’s structure, challenging misconceptions and correcting numerous anatomical errors.

This work laid the foundation for modern anatomy, shifting medicine toward empirical observation and directly influencing future generations of physicians and scientists.